A good Noise Gate such as the ISP Decimator G String

[DiffractionCircuit]

I owned and used an ISP Decimator G String with my 100W tube amp. They worked great together. I sold both to fund my Quad Cortex.

The G String has two inputs and outputs. The first I/O is for tracking the signal only; intended mostly for plugging your guitar straight in and going out. The second I/O is the noise reduction, which is based off of what the tracking circuit detects.

The request below mimics the function of the Decimator G String. Track guitar on the input, reduce noise elsewhere with a separate block in the chain.

Sidechain gate

a gate that reads the detect signal from selectable input, guitar DI. then you can put the block wherever, after reverbs/delays/amp. it opens with the clean DI signal but controlling as much lunacy as you want behind it.