Using the QC as a second amp/cab for stereo in my pedalboard/amp/cab rig

Hello! I have a large pedalboard and a few amps that I use and then a QC that I have only ever used standalone. I want to start using stereo amps and effects and was wondering if anyone has had any luck using the QC in this manner as just an amp/cab.

All pedals that go into the front of the amps would be split into the fronts and then all pedals into their respective effects loops. Would I just use send and return for my pedals that normally go in effects loops? Does anyone see any downfalls?

I like the idea of stereo tracking rhythm guitars and ambient parts.

Thanks!