When you create a preset , and select the MULTIOUT option , I assume that includes XLR and TS , left and Right , but if occasionally you have only TS or Only XLR , do you have to change the OUTPUT in the settings as a way to protect the output that is not plugged ?
I’m not sure what you want to protect the outputs from. If nothing is plugged in, you can just ignore them. They’ll be fine 
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I think is the fear of burn a output transformer of a tube amp that get projected to my digital stuff , I need to get over it I guess , I even think there is a a sensor or a switch there that mutes the output when unplugged
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Ah got it. Yeah that rule to not operate without an output load is specific to tube amps. With transistor based amps that is not a problem. And in this case we’re not even talking about high powered output to drive a speaker, but line level connections with much lower voltage/currents.
So you don’t need to worry about damaging anything.
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