Some worse than others, single coil pickups for as wonderful as they sound can have problems with noise or 60-cycle hum.
In some environments, particularly live venues, the noise can be very loud.
A feature I would find to be useful would be a hum-cancelling effect similar to the Ebtech/Morley Hum Eliminator that can be set at the I/O screen and saved in the Input Profile (Input Profile doesn’t exist at the time of this suggestion but is suggested here: Input Profile for different instruments )
This would allow the guitarist to turn on the hum cancelling globally for all presets/scenes that are using that Input Profile.
This would allow the musician to quickly turn on this feature for all of the instruments that are struggling with noise and leave it off for those that are not.