Had a weird noisy experience going straight into the PA

Had a gig on Saturday night. For some reason, when I went from Output 1 XLR to the PA, there was a wall of white noise. We eventually got some sound, although it was really quiet. Suddenly, it burst into life in the monitors and was fine for about 30 seconds of the opening song, then when I switched scenes it blasted out white noise again. The signals looked good on the QC and I’ve used it live a dozen times. I tried going directly into the amp they had in the backline from Out3/L but had the same problem. When I got home, I tested out my QC and it’s working fine.

Totally ruined the gig - I had to go and manually change between the clean and drive channels on the little combo, was missing all of my FX, a total disaster! We got through the set at least…

Anyone got any idea what the problem could have been? My first thoughts were an incompetent sound guy, or the QC wasn’t grounding through the PA, but that doesn’t explain why it was sounding bad through the amp too. Could it have been dirty power perhaps? I’m stumped but want to know what to try in case we ever play that venue again. TYIA