I think switching to a mono output could work just as well, although it may be a few extra taps if you are using both XLR and TRS outs and need to switch them both to mono. I like to be able to double tap one block on the grid and have the preset switch to mono. Of course, the trade off is consuming a space at the end of my chain.
There is also the option of using an empty mono IR block as described here: Global stereo/mono hack
It requires some discipline with your preset building to ensure you have no other IR blocks in that lane, but has the advantage of being able to toggle it for all presets via a global setting. I have not tried that method yet.