Plugin instances

Hey friends, I’ve recently jumped into the world of Amp Sims with Nolly and am looking for general advice on how to best use multiple instances of the plug in. For instance, when I dual track Rhythm guitars am I best having 2 separate plugins on each track or feeding them into 1 Stereo Bus with 1 plugin? In peoples experience does it make much of a difference to the Tone or CPU usage?


I’m curious about this too.
Personally, I’m used to play my dual-track guitars through a single stero instance, each guitar panned at 100% on a side.

I do it because it consumes less CPU than having two mono instances and for configuration practicality purpose.
But if we want to go for a less extreme panning, this usage might be very bad by combining two guitars in same saturation processes.